{"id":"https://openalex.org/W2102885665","doi":"https://doi.org/10.1093/bioinformatics/bts337","title":"SAAP-RRBS: streamlined analysis and annotation pipeline for reduced representation bisulfite sequencing","display_name":"SAAP-RRBS: streamlined analysis and annotation pipeline for reduced representation bisulfite sequencing","publication_year":2012,"publication_date":"2012-06-10","ids":{"openalex":"https://openalex.org/W2102885665","doi":"https://doi.org/10.1093/bioinformatics/bts337","mag":"2102885665","pmid":"https://pubmed.ncbi.nlm.nih.gov/22689387"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bts337","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts337","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/28/16/2180/16904452/bts337.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/28/16/2180/16904452/bts337.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067865294","display_name":"Zhifu Sun","orcid":"https://orcid.org/0000-0001-8461-7523"},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Zhifu Sun","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111996562","display_name":"Saurabh Baheti","orcid":"https://orcid.org/0000-0002-3564-7627"},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saurabh Baheti","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051222892","display_name":"Sumit Middha","orcid":"https://orcid.org/0000-0003-4135-6268"},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sumit Middha","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053119532","display_name":"Rahul Kanwar","orcid":"https://orcid.org/0000-0002-4575-8654"},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rahul Kanwar","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000223629","display_name":"Yuji Zhang","orcid":"https://orcid.org/0000-0002-5429-6762"},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuji Zhang","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100603917","display_name":"Xing Li","orcid":"https://orcid.org/0000-0003-0183-8000"},"institutions":[{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]},{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xing Li","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035951749","display_name":"Andreas S. Beutler","orcid":"https://orcid.org/0000-0002-2528-5204"},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andreas S. Beutler","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044058635","display_name":"Eric W. Klee","orcid":"https://orcid.org/0000-0003-2946-5795"},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Klee","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022178171","display_name":"Yan W. Asmann","orcid":"https://orcid.org/0000-0002-8896-2647"},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yan W. Asmann","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026692399","display_name":"E. Aubrey Thompson","orcid":"https://orcid.org/0000-0002-9001-4240"},"institutions":[{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]},{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. Aubrey Thompson","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071782757","display_name":"Jean\u2010Pierre Kocher","orcid":"https://orcid.org/0000-0002-0260-6773"},"institutions":[{"id":"https://openalex.org/I4390039329","display_name":"UNC Lineberger Comprehensive Cancer Center","ror":"https://ror.org/043ehm030","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I114027177","https://openalex.org/I4390039329"]},{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jean-Pierre A. Kocher","raw_affiliation_strings":["1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA"],"affiliations":[{"raw_affiliation_string":"1 Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, 2Department of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA and 3Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, FL 32224, USA","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5067865294"],"corresponding_institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039329"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":1.7418,"has_fulltext":true,"cited_by_count":68,"citation_normalized_percentile":{"value":0.8428132,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"28","issue":"16","first_page":"2180","last_page":"2181"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.7032673358917236},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6130639314651489},{"id":"https://openalex.org/keywords/bisulfite-sequencing","display_name":"Bisulfite sequencing","score":0.5992007255554199},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.515130877494812},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.48277583718299866},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.4823422133922577},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.44004929065704346},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.4019468426704407},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3941269516944885},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.3323720097541809},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2569807171821594},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.13815569877624512},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.12852609157562256},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.09024277329444885}],"concepts":[{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.7032673358917236},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6130639314651489},{"id":"https://openalex.org/C189235521","wikidata":"https://www.wikidata.org/wiki/Q4087270","display_name":"Bisulfite sequencing","level":5,"score":0.5992007255554199},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.515130877494812},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.48277583718299866},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.4823422133922577},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.44004929065704346},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.4019468426704407},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3941269516944885},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.3323720097541809},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2569807171821594},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13815569877624512},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.12852609157562256},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.09024277329444885},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013447","descriptor_name":"Sulfites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013447","descriptor_name":"Sulfites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013447","descriptor_name":"Sulfites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018899","descriptor_name":"CpG Islands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018899","descriptor_name":"CpG Islands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018899","descriptor_name":"CpG Islands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/bts337","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts337","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/28/16/2180/16904452/bts337.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:22689387","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22689387","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:europepmc.org:2418716","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3413387","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bts337","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts337","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/28/16/2180/16904452/bts337.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure","score":0.5400000214576721}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2102885665.pdf","grobid_xml":"https://content.openalex.org/works/W2102885665.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W1755052449","https://openalex.org/W2036897871","https://openalex.org/W2041259906","https://openalex.org/W2067130606","https://openalex.org/W2069796345","https://openalex.org/W2103810926","https://openalex.org/W2106889224","https://openalex.org/W2109715726","https://openalex.org/W2131232216","https://openalex.org/W2131374955","https://openalex.org/W2156165856"],"related_works":["https://openalex.org/W2361861616","https://openalex.org/W4390949414","https://openalex.org/W2950845984","https://openalex.org/W2900173251","https://openalex.org/W2757034914","https://openalex.org/W2467814536","https://openalex.org/W2126992172","https://openalex.org/W2787468300","https://openalex.org/W2960556654","https://openalex.org/W2103759706"],"abstract_inverted_index":{"SAAP-RRBS":[0],"is":[1],"freely":[2],"available":[3],"to":[4],"non-commercial":[5],"users":[6],"at":[7],"the":[8],"web":[9],"site":[10],"http://ndc.mayo.edu/mayo/research/biostat/stand-alone-packages.cfm.":[11]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4}],"updated_date":"2026-03-08T08:50:53.379069","created_date":"2025-10-10T00:00:00"}
