{"id":"https://openalex.org/W2470503807","doi":"https://doi.org/10.1109/tbme.2016.2585114","title":"Radiotherapy Planning Using an Improved Search Strategy in Particle Swarm Optimization","display_name":"Radiotherapy Planning Using an Improved Search Strategy in Particle Swarm Optimization","publication_year":2016,"publication_date":"2016-06-27","ids":{"openalex":"https://openalex.org/W2470503807","doi":"https://doi.org/10.1109/tbme.2016.2585114","mag":"2470503807"},"language":"en","primary_location":{"id":"doi:10.1109/tbme.2016.2585114","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2016.2585114","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5219950","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020305999","display_name":"Arezoo Modiri","orcid":null},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"education","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arezoo Modiri","raw_affiliation_strings":["Department of Radiation Oncology, University of Maryland, Baltimore, MD, USA","Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Maryland, Baltimore, MD, USA","institution_ids":["https://openalex.org/I126744593"]},{"raw_affiliation_string":"Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059684522","display_name":"Xuejun Gu","orcid":"https://orcid.org/0000-0001-6725-6906"},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"education","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xuejun Gu","raw_affiliation_strings":["Department of Radiation Oncology, University of Texas Southwestern Medical Center"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Texas Southwestern Medical Center","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009183142","display_name":"A Hagan","orcid":null},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"education","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron M. Hagan","raw_affiliation_strings":["Department of Radiation Oncology, University of Texas Southwestern Medical Center"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Texas Southwestern Medical Center","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048257046","display_name":"Amit Sawant","orcid":"https://orcid.org/0000-0002-3275-4160"},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"education","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amit Sawant","raw_affiliation_strings":["Department of Radiation Oncology, University of Texas Southwestern Medical Center","Department of Radiation Oncology, the University of Maryland"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, University of Texas Southwestern Medical Center","institution_ids":["https://openalex.org/I867280407"]},{"raw_affiliation_string":"Department of Radiation Oncology, the University of Maryland","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5020305999"],"corresponding_institution_ids":["https://openalex.org/I126744593","https://openalex.org/I867280407"],"apc_list":null,"apc_paid":null,"fwci":5.3986,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.95316282,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"64","issue":"5","first_page":"980","last_page":"989"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13123","display_name":"Advances in Oncology and Radiotherapy","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/particle-swarm-optimization","display_name":"Particle swarm optimization","score":0.7845836877822876},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4687037169933319},{"id":"https://openalex.org/keywords/radiation-therapy","display_name":"Radiation therapy","score":0.43047231435775757},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.33153408765792847},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.2160520851612091},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.14233559370040894},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.09763240814208984}],"concepts":[{"id":"https://openalex.org/C85617194","wikidata":"https://www.wikidata.org/wiki/Q2072794","display_name":"Particle swarm optimization","level":2,"score":0.7845836877822876},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4687037169933319},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.43047231435775757},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.33153408765792847},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2160520851612091},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.14233559370040894},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09763240814208984},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/tbme.2016.2585114","is_oa":false,"landing_page_url":"https://doi.org/10.1109/tbme.2016.2585114","pdf_url":null,"source":{"id":"https://openalex.org/S5240358","display_name":"IEEE Transactions on Biomedical Engineering","issn_l":"0018-9294","issn":["0018-9294","1558-2531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Transactions on Biomedical Engineering","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5219950","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5219950","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Biomed Eng","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5219950","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5219950","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Trans Biomed Eng","raw_type":"Text"},"sustainable_development_goals":[{"score":0.4399999976158142,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G6351412627","display_name":null,"funder_award_id":"R01CA169102","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320309603","display_name":"Varian Medical Systems","ror":"https://ror.org/05yab6874"},{"id":"https://openalex.org/F4320310169","display_name":"University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W256394748","https://openalex.org/W1189901287","https://openalex.org/W1484334610","https://openalex.org/W1569612970","https://openalex.org/W1595498733","https://openalex.org/W1966713553","https://openalex.org/W1971614725","https://openalex.org/W1980099932","https://openalex.org/W1999438941","https://openalex.org/W2013219706","https://openalex.org/W2020141781","https://openalex.org/W2033492551","https://openalex.org/W2033511209","https://openalex.org/W2035913072","https://openalex.org/W2036282507","https://openalex.org/W2037065460","https://openalex.org/W2037116662","https://openalex.org/W2042114136","https://openalex.org/W2045073901","https://openalex.org/W2049365279","https://openalex.org/W2061036312","https://openalex.org/W2067990745","https://openalex.org/W2068333777","https://openalex.org/W2068617023","https://openalex.org/W2072723582","https://openalex.org/W2073524083","https://openalex.org/W2078588198","https://openalex.org/W2081749411","https://openalex.org/W2084442756","https://openalex.org/W2094811672","https://openalex.org/W2101920731","https://openalex.org/W2109364787","https://openalex.org/W2122062060","https://openalex.org/W2126393454","https://openalex.org/W2137642415","https://openalex.org/W2139386984","https://openalex.org/W2159746573","https://openalex.org/W2169742862","https://openalex.org/W2326087240","https://openalex.org/W2344903343","https://openalex.org/W2485683853","https://openalex.org/W2533403688","https://openalex.org/W4293775970","https://openalex.org/W4300840064"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2382290278","https://openalex.org/W2478288626","https://openalex.org/W2350741829","https://openalex.org/W2530322880","https://openalex.org/W1596801655"],"abstract_inverted_index":{"Objective:":[0],"Evolutionary":[1],"stochastic":[2],"global":[3,177],"optimization":[4,38,89,144,205,219,239],"algorithms":[5],"are":[6,125],"widely":[7],"used":[8,108],"in":[9,66,179,225,241],"large-scale,":[10,217],"nonconvex":[11,218],"problems.":[12,244],"However,":[13],"enhancing":[14],"the":[15,52,80,157,176,197,204,238],"search":[16,194,199],"efficiency":[17,240],"and":[18,111,149,201,208],"repeatability":[19],"of":[20,64,118,182],"these":[21],"techniques":[22],"often":[23],"requires":[24],"well-customized":[25],"approaches.":[26],"This":[27],"study":[28],"investigates":[29],"one":[30],"such":[31],"approach.":[32,133],"Methods:":[33],"We":[34,102],"use":[35,57],"particle":[36],"swarm":[37,198],"(PSO)":[39],"algorithm":[40],"to":[41,56,74,79,159,167,174],"solve":[42],"a":[43,76,136,216,226],"4D":[44],"radiation":[45,92],"therapy":[46],"(RT)":[47],"inverse":[48],"planning":[49,214],"problem,":[50,220],"where":[51,221],"key":[53],"idea":[54],"is":[55,73,146,215,230],"respiratory":[58,100],"motion":[59],"as":[60],"an":[61],"additional":[62],"degree":[63],"freedom":[65],"lung":[67,121],"cancer":[68,122],"RT.":[69],"The":[70,152,191],"primary":[71],"goal":[72],"administer":[75],"lethal":[77],"dose":[78],"tumor":[81],"target":[82],"while":[83,162],"sparing":[84],"surrounding":[85],"healthy":[86],"tissue.":[87],"Our":[88,232],"iteratively":[90],"adjusts":[91],"fluence-weights":[93],"for":[94,210],"all":[95,99,170],"beam":[96],"apertures":[97],"across":[98,169],"phases.":[101],"implement":[103],"three":[104],"PSO-based":[105],"approaches:":[106],"conventionally":[107],"unconstrained,":[109],"hard-constrained,":[110],"our":[112],"proposed":[113,153,192,233],"virtual":[114,193],"search.":[115],"As":[116],"proof":[117],"concept,":[119],"five":[120],"patient":[123],"cases":[124,185],"optimized":[126],"over":[127,186],"ten":[128],"runs":[129],"using":[130],"each":[131],"PSO":[132],"For":[134],"comparison,":[135],"dynamically":[137],"penalized":[138],"likelihood":[139],"(DPL)":[140],"algorithm-a":[141],"popular":[142],"RT":[143,184,213],"technique":[145,154],"also":[147],"implemented":[148],"used.":[150],"Results:":[151],"significantly":[155,187],"improves":[156,203],"robustness":[158,209],"random":[160],"initialization":[161],"requiring":[163],"fewer":[164],"iteration":[165],"cycles":[166],"converge":[168],"cases.":[171],"DPL":[172],"manages":[173],"find":[175],"optimum":[178],"2":[180],"out":[181],"5":[183],"more":[188],"iterations.":[189],"Conclusion:":[190],"approach":[195,234],"boosts":[196],"efficiency,":[200],"consequently,":[202],"convergence":[206],"rate":[207],"PSO.":[211],"Significance:":[212],"finding":[222],"optimal":[223],"solutions":[224],"clinically":[227],"practical":[228],"time":[229],"critical.":[231],"can":[235],"potentially":[236],"improve":[237],"similar":[242],"time-sensitive":[243]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2016-07-22T00:00:00"}