{"id":"https://openalex.org/W4285004687","doi":"https://doi.org/10.1145/3535694.3535713","title":"The Development of an Electrochemical Biosensor to Detect Congenital Asthma","display_name":"The Development of an Electrochemical Biosensor to Detect Congenital Asthma","publication_year":2022,"publication_date":"2022-04-20","ids":{"openalex":"https://openalex.org/W4285004687","doi":"https://doi.org/10.1145/3535694.3535713"},"language":"en","primary_location":{"id":"doi:10.1145/3535694.3535713","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3535694.3535713","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 12th International Conference on Biomedical Engineering and Technology","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049563835","display_name":"B.C. Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Boxuan Zhang","raw_affiliation_strings":["Faculty of Biology, University of Ottawa, Canada"],"affiliations":[{"raw_affiliation_string":"Faculty of Biology, University of Ottawa, Canada","institution_ids":["https://openalex.org/I153718931"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5049563835"],"corresponding_institution_ids":["https://openalex.org/I153718931"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.06551603,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"115","last_page":"120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.8666999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.8666999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.8004999756813049,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.7440999746322632,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asthma","display_name":"Asthma","score":0.8149261474609375},{"id":"https://openalex.org/keywords/biosensor","display_name":"Biosensor","score":0.48281916975975037},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.4414719343185425},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.41442063450813293},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.35194313526153564},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.33369213342666626},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.32359635829925537},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.31440651416778564},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.27437835931777954},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.23901060223579407},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.09671321511268616}],"concepts":[{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.8149261474609375},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.48281916975975037},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.4414719343185425},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.41442063450813293},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.35194313526153564},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33369213342666626},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32359635829925537},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.31440651416778564},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.27437835931777954},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.23901060223579407},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.09671321511268616},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1145/3535694.3535713","is_oa":false,"landing_page_url":"https://doi.org/10.1145/3535694.3535713","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the 12th International Conference on Biomedical Engineering and Technology","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","score":0.6800000071525574,"display_name":"Affordable and clean energy"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W2012269927","https://openalex.org/W2754545145","https://openalex.org/W2986335621","https://openalex.org/W3137672435"],"related_works":["https://openalex.org/W2046430340","https://openalex.org/W2322026400","https://openalex.org/W2383021773","https://openalex.org/W4206515393","https://openalex.org/W1990396141","https://openalex.org/W2056670287","https://openalex.org/W1929958295","https://openalex.org/W2226641048","https://openalex.org/W2002555800","https://openalex.org/W2021425015"],"abstract_inverted_index":{"The":[0],"research":[1],"is":[2,16,47,59],"about":[3],"the":[4,48,73,96,99],"development":[5],"of":[6],"an":[7,60],"electrochemical":[8],"biosensor":[9],"to":[10,43,52,78,112],"detect":[11,53,113],"congenital":[12,54,88,102],"asthma.":[13,55,89],"This":[14],"disease":[15],"a":[17,65],"long-term":[18],"inflammatory":[19],"disease,":[20],"and":[21,41,82,86],"most":[22],"people":[23],"are":[24,110],"not":[25],"paying":[26],"attention.":[27],"Electrochemical":[28],"biosensors":[29],"have":[30,70],"multiple":[31],"advantages":[32],"like":[33],"low":[34],"cost,":[35],"rapid":[36],"response,":[37],"simplicity,":[38],"high":[39],"sensitivity":[40],"ease":[42],"use.":[44],"Therefore,":[45,90],"it":[46],"best":[49],"method":[50],"used":[51],"Metalloproteinase":[56],"33":[57],"(ADAM33)":[58],"asthma":[61,103],"susceptibility":[62],"gene":[63],"in":[64,95],"human's":[66],"chromosome.":[67],"Multiple":[68],"studies":[69],"shown":[71],"that":[72],"ADAM33\u2019s":[74],"overexpression":[75],"could":[76],"lead":[77],"two":[79,93,108],"SNPs":[80,94,115],"(rs2280090":[81],"rs2280091)":[83],"mutations":[84],"appearing":[85],"causing":[87],"discovering":[91],"these":[92],"body":[97,100],"represent":[98],"has":[101],"possible.":[104],"In":[105],"this":[106],"study,":[107],"methods":[109],"showed":[111],"pathologies":[114],"from":[116],"unknown":[117],"samples.":[118]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
