DKK2: Difference between revisions
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| summary_text = This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).<ref name="entrez" |
| summary_text = This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).<ref name="entrez" /> |
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Revision as of 23:25, 26 December 2012
Template:PBB Dickkopf-related protein 2 is a protein that in humans is encoded by the DKK2 gene.[1][2]
References
- ^ Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA (1999). "Functional and structural diversity of the human Dickkopf gene family". Gene. 238 (2): 301–13. doi:10.1016/S0378-1119(99)00365-0. PMID 10570958.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ "Entrez Gene: DKK2 dickkopf homolog 2 (Xenopus laevis)".
Further reading
 | This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it. |