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Revision as of 22:09, 17 March 2013
Template:PBB GIPC PDZ domain containing family, member 1 (GIPC1) is a protein that in humans is encoded by the GIPC1 gene.[1][2][3]
Interactions
GIPC1 has been shown to interact with Beta-1 adrenergic receptor,[4] ITGA5,[5] ITGA6,[5] TPBG,[6] RGS19,[7] TYRP1,[8] GLUT1,[9] Actinin, alpha 1,[9] KIF1B,[9] LRP2,[10][11][12] Luteinizing hormone/choriogonadotropin receptor,[13] LRP1[10] and MYO6.[14][15]
See also
GIPC PDZ domain containing family, member 2, GIPC2
GIPC PDZ domain containing family, member 3, GIPC3
References
- ^ De Vries L, Lou X, Zhao G, Zheng B, Farquhar MG (1998). "GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP". Proc Natl Acad Sci U S A. 95 (21): 12340–5. doi:10.1073/pnas.95.21.12340. PMC 22833. PMID 9770488.
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ignored (help)CS1 maint: multiple names: authors list (link) - ^ Rousset R, Fabre S, Desbois C, Bantignies F, Jalinot P (1998). "The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins". Oncogene. 16 (5): 643–54. doi:10.1038/sj.onc.1201567. PMID 9482110.
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ignored (help)CS1 maint: multiple names: authors list (link) - ^ "Entrez Gene: GIPC1 GIPC PDZ domain containing family, member 1".
- ^ Hu, Liaoyuan A (2003). "GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation". J. Biol. Chem. 278 (28). United States: 26295–301. doi:10.1074/jbc.M212352200. ISSN 0021-9258. PMID 12724327.
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ignored (help)CS1 maint: unflagged free DOI (link) - ^ a b Tani, T T (2001). "PDZ interaction sites in integrin alpha subunits. T14853, TIP/GIPC binds to a type I recognition sequence in alpha 6A/alpha 5 and a novel sequence in alpha 6B". J. Biol. Chem. 276 (39). United States: 36535–42. doi:10.1074/jbc.M105785200. ISSN 0021-9258. PMID 11479315.
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ignored (help)CS1 maint: unflagged free DOI (link) - ^ Awan, Abida (2002). "5T4 interacts with TIP-2/GIPC, a PDZ protein, with implications for metastasis". Biochem. Biophys. Res. Commun. 290 (3). United States: 1030–6. doi:10.1006/bbrc.2001.6288. ISSN 0006-291X. PMID 11798178.
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ignored (help) - ^ Lou, X (2001). "GIPC and GAIP form a complex with TrkA: a putative link between G protein and receptor tyrosine kinase pathways". Mol. Biol. Cell. 12 (3). United States: 615–27. ISSN 1059-1524. PMC 30968. PMID 11251075.
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ignored (help) - ^ Liu, T F (2001). "PDZ domain protein GIPC interacts with the cytoplasmic tail of melanosomal membrane protein gp75 (tyrosinase-related protein-1)". J. Biol. Chem. 276 (38). United States: 35768–77. doi:10.1074/jbc.M103585200. ISSN 0021-9258. PMID 11441007.
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ignored (help)CS1 maint: unflagged free DOI (link) - ^ a b c Bunn, R C (1999). "Protein interactions with the glucose transporter binding protein GLUT1CBP that provide a link between GLUT1 and the cytoskeleton". Mol. Biol. Cell. 10 (4). UNITED STATES: 819–32. ISSN 1059-1524. PMC 25204. PMID 10198040.
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ignored (help) - ^ a b Gotthardt, M (2000). "Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction". J. Biol. Chem. 275 (33). UNITED STATES: 25616–24. doi:10.1074/jbc.M000955200. ISSN 0021-9258. PMID 10827173.
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ignored (help)CS1 maint: unflagged free DOI (link) - ^ Petersen, Helle Heibroch (2003). "Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule". J. Cell. Sci. 116 (Pt 3). England: 453–61. doi:10.1242/jcs.00243. ISSN 0021-9533. PMID 12508107.
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ignored (help) - ^ Lou, Xiaojing (2002). "GAIP, GIPC and Galphai3 are concentrated in endocytic compartments of proximal tubule cells: putative role in regulating megalin's function". J. Am. Soc. Nephrol. 13 (4). United States: 918–27. ISSN 1046-6673. PMID 11912251.
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ignored (help) - ^ Hirakawa, Takashi (2003). "GIPC binds to the human lutropin receptor (hLHR) through an unusual PDZ domain binding motif, and it regulates the sorting of the internalized human choriogonadotropin and the density of cell surface hLHR". J. Biol. Chem. 278 (49). United States: 49348–57. doi:10.1074/jbc.M306557200. ISSN 0021-9258. PMID 14507927.
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Further reading