XRN1 (gene): Difference between revisions
Content deleted Content added
m grammatical problem. delete "is" before "hydrolyses" |
m Journal cites, added 1 PMID, added 1 PMC using AWB (12142) |
||
| Line 18: | Line 18: | ||
|LocusSupplementaryData= |
|LocusSupplementaryData= |
||
}} |
}} |
||
'''5'-3' exoribonuclease 1''' ('''XRN1''') is an [[exoribonuclease]] enzyme encoded in humans by the ''XRN1'' gene. This enzyme hydrolyses [[RNA]] in the 5’ to 3’ direction.<ref>{{cite journal|last1=Mullen|first1=T. E.|last2=Marzluff|first2=W. F.|title=Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'|journal=Genes & Development|date=1 January 2008|volume=22|issue=1|pages=50–65|doi=10.1101/gad.1622708|url=http://genesdev.cshlp.org/content/22/1/50.full}}</ref> |
'''5'-3' exoribonuclease 1''' ('''XRN1''') is an [[exoribonuclease]] enzyme encoded in humans by the ''XRN1'' gene. This enzyme hydrolyses [[RNA]] in the 5’ to 3’ direction.<ref>{{cite journal|last1=Mullen|first1=T. E.|last2=Marzluff|first2=W. F.|title=Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'|journal=Genes & Development|date=1 January 2008|volume=22|issue=1|pages=50–65|doi=10.1101/gad.1622708|url=http://genesdev.cshlp.org/content/22/1/50.full|pmid=18172165|pmc=2151014}}</ref> |
||
==References== |
==References== |
||
| Line 27: | Line 27: | ||
[[Category:EC 3.1]] |
[[Category:EC 3.1]] |
||
{{biochem-stub}} |
{{biochem-stub}} |
||
Revision as of 16:29, 6 February 2017
| 5'-3' exoribonuclease 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | XRN1 | ||||||
| NCBI gene | 54464 | ||||||
| HGNC | 30654 | ||||||
| OMIM | 607994 | ||||||
| RefSeq | NM_019001 | ||||||
| UniProt | Q8IZH2 | ||||||
| Other data | |||||||
| Locus | Chr. 3 q23 | ||||||
| |||||||
5'-3' exoribonuclease 1 (XRN1) is an exoribonuclease enzyme encoded in humans by the XRN1 gene. This enzyme hydrolyses RNA in the 5’ to 3’ direction.[1]
References
- ^ Mullen, T. E.; Marzluff, W. F. (1 January 2008). "Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'". Genes & Development. 22 (1): 50–65. doi:10.1101/gad.1622708. PMC 2151014. PMID 18172165.
External links
- XRN1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
.svg){kind=small} | This biochemistry article is a stub. You can help Wikipedia by expanding it. |