Lihat sumber Homoklorsiklizin

{{Drugbox
| IUPAC_name = 1-[(4-klorofenil)-fenilmetil]-4-metil-1,4-diazepana
| image = Homochlorcyclizine.svg

<!--Clinical data-->
| tradename =  
| Drugs.com = {{drugs.com|international|homochlorcyclizine}}
| pregnancy_category =  
| legal_status = Rx-only
| routes_of_administration = Oral

<!--Pharmacokinetic data-->
| bioavailability =  
| metabolism =  
| elimination_half-life =  
| excretion =

<!--Identifiers-->
| CAS_number = 848-53-3
| ATC_prefix = none
| ATC_suffix =  
| PubChem = 3627
| ChemSpiderID = 3501
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = N5MVC31W2N
| KEGG = D08041
| ChEMBL = 151447

<!--Chemical data-->
| C=19 | H=23 | Cl=1 | N=2 
| smiles = CN1CCCN(CC1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
}}

'''Homoklorsiklizin''' ([[Nama Generik Internasional|INN]]) adalah [[antihistamin]] golongan difenilmetilpiperazin yang telah dipasarkan di Jepang sejak tahun 1965.<ref>{{cite web |url=http://di.eisai.co.jp/di/EPI/HC_T_EPI.pdf |title=Homoclomin Tablets 10&nbsp;mg |date=December 2007 |publisher=[[Eisai Co.]] |access-date=2008-07-29}} {{Dead link|date=October 2010|bot=H3llBot}}</ref> Obat ini digunakan dalam pengobatan [[alergi]] dan kondisi lainnya. Obat ini juga memiliki beberapa sifat [[antikolinergik]], [[antagonis dopamin|antidopaminergik]], dan antiserotonergik.<ref name="pmid9193868">{{cite journal |vauthors=Haraguchi K, Ito K, Kotaki H, Sawada Y, Iga T | title = Prediction of drug-induced catalepsy based on dopamine D1, D2, and muscarinic acetylcholine receptor occupancies | journal = Drug Metabolism and Disposition | volume = 25 | issue = 6 | pages = 675–84 |date=June 1997 | pmid = 9193868 | url = http://dmd.aspetjournals.org/cgi/pmidlookup?view=long&pmid=9193868}}</ref><ref name="pmid14409112">{{cite journal |vauthors=KIMURA ET, YOUNG PR, RICHARDS RK | title = Pharmacologic properties of N-p-chloro-benzhydryl-N'-methyl homopiperazine dihydrochloride (homochlorcyclizine; SA-97), a serotonin antagonist | journal = Journal of Allergy | volume = 31 | pages = 237–47 | year = 1960 | doi = 10.1016/0021-8707(60)90052-6 | pmid = 14409112 }}</ref>

== Referensi ==
{{Reflist}}
[[Kategori:Antagonis reseptor H1]]
[[Kategori:Senyawa 4-klorofenil]]
[[Kategori:Diazepana]]