Iksabepilon

Iksabepilon
Nama sistematis (IUPAC)
	(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-1,5,7,; 9,9-pentamethyl-14-[(E)-1-(2-methyl-1,3-thiazol-; 4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14.1.0]; heptadecane-8,12-dione
Data klinis
Nama dagang	Ixempra
AHFS/Drugs.com	monograph
MedlinePlus	a608042
Data lisensi	US Daily Med:pranala
Kat. kehamilan	D(US)
Status hukum	℞-only (US)
Rute	Intravenous infusion
Data farmakokinetik
Bioavailabilitas	N/A
Ikatan protein	67 to 77%
Metabolisme	Extensive, hepatic, CYP3A4-mediated
Waktu paruh	52 hours
Ekskresi	Fecal (mostly) and renal
Pengenal
Nomor CAS	219989-84-1
Kode ATC	L01DC04
PubChem	CID 6445540
Ligan IUPHAR	6824
DrugBank	DB04845
ChemSpider	20145579
UNII	K27005NP0A
KEGG	D04645
ChEMBL	CHEMBL1201752
Sinonim	Azaepothilone B
Data kimia
Rumus	C27H42N2O5S
SMILES	eMolecules & PubChem
	InChI InChI=1S/C27H42N2O5S/c1-15-9-8-10-27(7)22(34-27)12-20(16(2)11-19-14-35-18(4)28-19)29-23(31)13-21(30)26(5,6)25(33)17(3)24(15)32/h11,14-15,17,20-22,24,30,32H,8-10,12-13H2,1-7H3,(H,29,31)/b16-11+/t15-,17+,20-,21-,22-,24-,27+/m0/s1 ; Key:FABUFPQFXZVHFB-PVYNADRNSA-N ;

Iksabepilon (INN; juga dikenal sebagai azaepothilone B, nama kode BMS-247550) adalah obat farmasi yang dikembangkan oleh Bristol-Myers Squibb sebagai obat kemoterapi untuk kanker.^[1]

^ "More information on cancer drugs". www.cancer.org.

[1] "More information on cancer drugs". www.cancer.org.

[1]