Droksikam – razlika između verzija
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| drug_name = Droksikam |
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| [[Rastvorljivost]]<ref>{{cite pmid|11749573|noedit}}</ref> (''logS'', log(''mol/L'')) || -3,4 |
| [[Rastvorljivost]]<ref>{{cite pmid|11749573|noedit}}</ref> (''logS'', log(''mol/L'')) || -3,4 |
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| [[Polarna površina molekula|Polarna površina]]<ref>{{cite pmid|11020286|noedit}}</ref> (''PSA'', [[ |
| [[Polarna površina molekula|Polarna površina]]<ref>{{cite pmid|11020286|noedit}}</ref> (''PSA'', [[Angstrem (jedinica)|''Å''<sup>2</sup>]]) || 105,3 |
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* {{FoyePrinciplesMedChem6th}} |
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== Vanjske veze == |
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{{Portal-lat|Medicina|Hemija}} |
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{{Commonscat-lat|Droxicam}} |
{{Commonscat-lat|Droxicam}} |
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* [http://www.drugbank.ca/drugs/ Droxicam] |
* [http://www.drugbank.ca/drugs/ Droxicam] |
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Aktualna verzija od 19. decembra 2024. u 20:18
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| Klinički podaci | |||
|---|---|---|---|
| AHFS/Drugs.com | Monografija | ||
| Identifikatori | |||
| ATC kod | M01AC04 | ||
| PubChem[1][2] | 65679 | ||
| UNII | F24ADO1E2D 
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| KEGG[3] | D07267
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| Hemijski podaci | |||
| Formula | C16H11N3O5S | ||
| Mol. masa | 357,341 | ||
| SMILES | eMolekuli & PubHem | ||
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| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
Droksikam je organsko jedinjenje, koje sadrži 16 atoma ugljenika i ima molekulsku masu od 357,341 Da.
| Osobina | Vrednost |
|---|---|
| Broj akceptora vodonika | 6 |
| Broj donora vodonika | 0 |
| Broj rotacionih veza | 1 |
| Particioni koeficijent[4] (ALogP) | 1,1 |
| Rastvorljivost[5] (logS, log(mol/L)) | -3,4 |
| Polarna površina[6] (PSA, Å2) | 105,3 |
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
- ↑ Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A 102: 3762-3772. DOI:10.1021/jp980230o.
- ↑ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488-1493. DOI:10.1021/ci000392t. PMID 11749573.
- ↑ Ertl P., Rohde B., Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714-3717. DOI:10.1021/jm000942e. PMID 11020286.
- Hardman JG, Limbird LE, Gilman AG. (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10 izd.). New York: McGraw-Hill. DOI:10.1036/0071422803. ISBN 0-07-135469-7.
- Thomas L. Lemke, David A. Williams, ur. (2007). Foye's Principles of Medicinal Chemistry (6 izd.). Baltimore: Lippincott Willams & Wilkins. ISBN 0-7817-6879-9.
