- She declined to appear at the Oscar ceremonies the year she won her award for "Virginia Woolf".
- Although she and Gerry Mulligan referred to each other as husband and wife for years, she eventually said that they had never married.
- Suffered a miscarriage at four months pregnant in December 1965 during the filming of Who's Afraid of Virginia Woolf? (1966).
- A dedicated exponent of the 'Method' technique via the Actor's Studio, her physical neuroticisms could either captivate or repel audiences.
- Appeared in a stage production of "Cat on a Hot Tin Roof" as Maggie the Cat, a role previously played by her "Who's Afraid of Virginia Woolf" co-star Elizabeth Taylor in the film version.
- Her brother Frank Dennis (1929-2017) was a structural engineer and Marine Corps veteran of both World War II and the Korean War.
- Awarded the coveted Theatre World Award for best Broadway debut in 1961.
- She won two consecutive Tony awards, in 1963 as Best Supporting or Featured Actress (Dramatic) for "A Thousand Clowns" and in 1964 as Best Actress (Dramatic) for "Any Wednesday," which eventually led to her Oscar-winning film performance in Who's Afraid of Virginia Woolf? (1966).
- According to a 2018 profile of former fiancée Eric Roberts in Vanity Fair, their engagement ended over Miss Dennis' refusal to start an animal shelter for some 100 stray cats living in the couple's shared home. She gave back the ring when he moved out.
- Sandy is one of 6 performers to win acting Tonys in back-to-back years. She won in 1963 for "A Thousand Clowns"(Featured Actress in a Play) and in 1964 for "Any Wednesday"(Lead Actress in a Play). The others are Shirley Booth (1949/50), Gwen Verdon (1958/59), Stephen Spinella (1993/94), Judith Light (2012/13), and Laurie Metcalf (2017/18).
- She studied drama at HB Studio in Greenwich Village in New York City.
- Parents were quite young (17 and 22) when her elder brother was born, hence why they waited eight years to have Sandy.
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