Goofs

(at around 22 mins) When the characters first enter the space station, the artificial gravity briefly turns on and then off again. Shortly thereafter, they enter a room where several objects are hovering in mid-air. If the objects had momentum immediately after the gravity switched off they should be moving on a trajectory, and if not they should still be against the floor. Either way, they should not be unmoving several feet off the floor.

(at around 57 mins) When Rain, Andy and Tyler had to go through the room filled with face-huggers, the temperature was raised to body temp, as temperature is one of the ways face-huggers track people, in addition to movement. As soon as the doors were opened, the room temperature would have immediately started dropping, making the effort meaningless.

(min 22) The characters are crawling though a vent with great difficulty, after boarding the station. They see a dead rat floating in the air revealing a lack of gravity in the station. The fact that all three characters are dragging themselves across the floor of the vent while in zero gravity is contrary. They should be floating through the vent.

They were told they had another 5 years service to do due to low numbers of workers. It doubled to 24000 hours (additional 12000); yet In reality 12000 hours is closer to 3 years - assuming they don't have a great holiday package and an 8 hour day.

At 56:06 the thermostat is set to 98.6° F to render humans invisible to the face-huggers, but human skin temperature is typically a few degrees cooler and varies depending upon the region of the body.

No explanation is given as to how the company scientists on Romulus reverse-engineered the alien to make facehuggers (and seemingly without eggs too). Not even the far more advanced scientists over 200 years into the future in Alien Resurrection (1997) could do that, they had to clone Ripley in order to get the queen alien embryo from her and enable it to produce eggs in order to produce facehuggers and subsequently full-size aliens. This suggests there is a queen somewhere on the station, but if there is she isn't shown or mentioned.

David used Black Goo to create his Protomorph prior to Alien: Covenant (2017). The Renaissance scientists would have to just extract Black Goo from "Big Chap" and do the same thing. The research on the Black Goo was destroyed with the Renaissance Space Station in this movie which explains why it was never replicated later.

Since this movie takes place between Alien (1979) and Aliens (1986) and it is shown that the Weyland-Yutani Corporation already did some extensive research on the Xenomorphs, they had no reason to send Ripley to LV-426 in Aliens, because by that point they already knew what they would find and most likely knew more about the species than Ripley did. However, the project was in all probability top secret so Burke, who was not a part of weapon division, wouldn't have known about it.

The mining colony is on a planet with Saturn-like rings on it. But these can only form in a stable way on planets whose gravity is far far greater than Earth. If most of the mining operation is extremely deep underground, this might still work, but it would be unfeasible if the mines were near the surface of the planet.

Correction: While planetary rings most commonly exist around gas giants they can and do exist around smaller rocky planets. The New Horizons probe revealed several dwarf planets in our own solar system have rings including Chariklo, Chiron, Haumea and Quaoar. Additionally evidence has been found indicating Earth may of had a ring system for at least 40 million years during the Ordovician period about 466 million years ago which originated from a large meteor cluster that passed near Earth getting caught in Earth's gravity well; evidence for this ring comes from impact craters from the Ordovician period appearing to cluster in a distinctive band around the Earth's equator.

(at around 1h 28 mins) In zero gravity, liquids form up into blobs and spheres due to surface tension. When Rain shoots the Xenomorphs in zero gravity, their blood stays stretched out and acts unrealistically.

Correction: This would be true of most Newtonian fluids, but as Rook stated he found that the Xenomorph blood contained non-Newtonian fluids, the blood's behavior is very realistic for a non-Newtonian fluid in zero gravity; in fact human blood is also non-Newtonian. Which are fluids that do not follow Newton's laws of viscosity, instead having a variable viscosity dependent on stress and force; in other words they become more fluid when in motion and more solid when sitting still, especially when compacted, ketchup being a good example. Non-Newtonian fluids behave strangely in zero gravity, since their viscosity isn't constant, surface tension causes them to behave differently, displaying viscosity changes due to sheer pressure even more prominently. Meaning instead of forming into spherical blobs it would become more fluid when gently disturbed but quickly solidify when impacted, like being hit by a bullet. Explaining why the Xenomorph's blood became very compacted together when they were initially shot but quickly spread out becoming extremely fluid as the centrifugal force of the station rotating gently acted on the blood, which is why it began to spread out in spiral shapes, reflecting the motion of the station. Although if the blood was allowed to loose its momentum and the station became stationary and ceased rotating then its surface tension would cause it to form into spheres, but only when no longer acted on by an external force.

No explanation is given as to how the probe found a xenomorph within the wreckage of the Nostromo. There was only one alien onboard the Nostromo, which survived the destruction of the ship only to be blown out of the shuttle's airlock by Ripley and incinerated in the shuttle's engine thrusters. To suggest the specimen survived that is ridiculous since the aliens are not indestructible and it has already been established that they can be killed by bullets and flamethrowers, or even by running them over in armoured wheeled vehicles (all of which happened in Aliens (1986)).

At the time, humans had yet to encounter and fully document Xenomorphs. There would be no way of knowing how durable the "perfect organisms" were.

(at around 2 mins) At the start of the film, a probe finds parts of the wreckage of the Nostromo floating in space near Zeta² Reticuli following its destruction a couple of decades earlier at the end of Alien (1979). Despite it being dubious there would be any wreckage left after what was such a monumental explosion, any parts of the ship that were not vaporised would not be simply floating in space around the area the explosion happened decades later. The force of the Nostromo's self destruct would have projected remnants of it in all directions at considerable speed, and since this is the vacuum of space, the remnants wouldn't slow down, they would simply keep flying through space at speed.

Equipment Visible at 1:43:50-54 - Rain is seen running barefoot on metal grid-mesh/grated flooring, adhesive medical tape can be seen strapped to the bottom of her feet to prevent injury from the flooring.

In the opening and end scene, when space and stars are shown, the stars are twinkling. This is incorrect. It is the oxygen of the earth that causes that effect, one of the reasons that scientists want telescopes in outer space--nothing to distort the image.

(at around 45 mins) Rook has no way of knowing there was a sole survivor or that Ripley had blown it out the Air Lock. Ripley's log at the end of the movie never mentions blowing it out the airlock, or that it was even in the escape ship. But additionally this wasn't a transmission that Ripley made, only a log. If it was a transmission then why wouldn't she wake herself up in 6 weeks when she reached the frontier to broadcast more reports to get picked up sooner instead of floating in space for 50+ years.

When the Corbalen switched from auto pilot to manual, it suddenly coasts to a stop when in reality, in space, there would be no gravity to stop it. The Corbalen should therefore have continued moving until someone manually braked her.

Andy is Weyland/Yutani proprietary tech, how is Rain allowed to have that on a W/Y mining world? They would definitely want that back. To decommission, or have destroyed at the very least if it is obsolete. There is no way they would allow some skid row teen go around using it to access their systems. Much less a top super secret alien research station.

(at around 6 mins) In the opening there is a reference to the population of the mining town of under 3000; yet In the streets shopping there were around 3000.