Name Of Drug Classification and Indications Contraindication Adverse Reactions Nursing Monitoring Parameters

Mechanism of Responsibilities
Action

Generic Name: Classification: Moderate to Severe Special Senses:

GENTAMICIN ANTIINFECTIVE; Infection -History of Ototoxicity (vestibular  Note: Dosages are  Perform C&S and renal
SULFATE AMINOGLYCOSIDE hypersensitivity to or disturbances, impaired generally adjusted to function prior to first dose
ANTIBIOTIC Acute Pelvic toxic reaction with any hearing), optic neuritis. maintain peak serum and periodically during
Inflammatory aminoglycoside CNS: neuromuscular gentamicin therapy; therapy may begin
Brand Name: antibiotic. Safe use blockade: skeletal concentrations of 4– 10 pending test results.
Disease g/mL, and trough
Garamycin, Action: during pregnancy muscle weakness, Determine creatinine
Garamycin concentrations of 1–2
Prophylaxis of (category C) or lactation apnea, respiratory clearance and serum drug
g/mL. Peak
Ophthalmic, Broad-spectrum Bacterial is not established paralysis (high doses); concentrations at frequent
concentrations above
Genoptic aminoglycoside arachnoiditis 12 g/mL and trough intervals, particularly for
Endocarditis
antibiotic derived (intrathecal use). concentrations above 2 patients with impaired renal
Dosage: 2 mg from CV: hypotension or g/mL are associated function, infants (renal
Micromonospora hypertension. with toxicity. immaturity), older adults,
Frequency: purpurea. Action is GI: Nausea, vomiting,  Draw blood patients receiving high doses
q8h usually transient increase in specimens for peak or therapy beyond 10 d,
bacteriocidal. AST, ALT, and serum serum gentamicin patients with fever or
LDH and bilirubin; concentration 30 min– extensive burns, edema,
hepatomegaly, 1h after IM obesity.
splenomegaly. administration, and 30
Other: Local irritation min after completion of
a 30–60 min IV
and pain following IM
infusion. Draw blood
use; thrombophlebitis, specimens for trough
abscess, levels just before the
superinfections, next IM or IV dose. Use
syndrome of nonheparinized tubes
hypocalcemia (tetany, to collect blood.
weakness,
hypokalemia,
Name Of Drug Classification and Indications Contraindication Adverse Reactions Nursing Monitoring Parameters
Mechanism of Responsibilities
Action
➢ Patients should
Generic Name: Classification: Treatment of This medication may be counseled that
Amikacin ANTIBIOTIC infections A history of cause nausea, antibacterial  Perform C&S and renal
caused by hypersensitivity to vomiting or drugs including function prior to first dose
AMINOGLYCOSIDE susceptible Amikacin is a weakness as your Amikacin should and periodically during
strains of contraindication body adjusts to the only be used to therapy; therapy may begin
Brand Name: microorganism for its use. A medication. If these treat bacterial pending test results.
Amikin Action: Determine creatinine
s, especially history of effects continue or infections.
Inhibits clearance and serum drug
gram-negative hypersensitivity or become severe, ➢ Patients should
Dosage: 2 mg production of concentrations at frequent
bacteria. serious toxic inform your doctor. be told that
bacterial intervals, particularly for
reactions to This medication can although it is
Frequency: protein, causing patients with impaired renal
aminoglycosides cause hearing loss common to feel
q8h bacterial cell function, infants (renal
may or kidney damage better early in the
death. immaturity), older adults,
contraindicate the especially if used in course of therapy,
patients receiving high doses
use of any other high doses or for the medication
or therapy beyond 10 d,
aminoglycoside prolonged periods of should be taken
patients with fever or
because of the time. It is important exactly as extensive burns, edema,
known cross- the proper dose be directed. obesity.
sensitivities of used. The site where ➢ Skipping doses or
patients to drugs the injection is given not completing
in this class. may be red and the full course of
irritated for a few therapy may
days. Notify your decrease the
doctor if the effectiveness of
irritation continues the immediate
or becomes worse. treatment