Assignment Question Bank
Pharmaceutical Analysis_BP102TP
UNIT 01
1. Define: Normality, Molality, Mole fraction, Accuracy, Precision, Titrant, Stoichiometric end point,
Significant figures, Primary standards
2. Explain primary and secondary standards with example. Write a note on Preparation and standardization
of molar and normal solutions of hydrochloric acid and sulphuric acid.
3. Write a detailed note on classification of analytical method.
4. Define Error. Describe the methods of minimization of errors.
5. Monograph of Indian Pharmacopoeia
6. Define, ideal characteristic and give suitable example of primary standard
7. Define validation. Explain validation parameters
8. Write a note on sampling techniques
9. Discuss the principle and reaction involved in limit test of Iron as per IP.
10. Classify Errors and explain accuracy and precision in detail.
UNIT 02
1. Explain in brief various acid base theories.
2. Explain end point detection method in acid base titration
3. What is hydrolysis? Derive equation for finding pH of aqueous solution of salt of weak acid and strong
base
4. Write a note on solvent, titrant and indicator used for weak acid & weak base in non-aqueous titration
5. Explain the estimation of sodium benzoate by non-aqueous titration
6. What is buffer solution? Explain types of buffer solution, preparation of buffer solution, buffer action.
7. Explain Buffer in detail. Write equation to calculate pH of buffer solution.
8. Discuss differentiating solvents and leveling solvents
9. 100 ml of 0.1M acetic acid is titrated with 0.1 M sodium hydroxide. Calculate the pH of solution when following
volume of NaOH is added, 1) 0 ml, 2) 50 ml, 3) 99 ml, 4) 100 ml, 5) 101 ml. Ka of acetic acid = 1.8 *10 -5. Draw
neutralization curve of it.
10. Discuss in brief various solvents used in non-aqueous titration
UNIT 03
1. Enlist the end point detection methods in precipitation titration. Explain mohr’s method in detail
2. Write a note on Vollhard method / Fajan Method.
3. Give note on masking and demasking agent in complexometric titration
4. Write a note on different types on complexometric titrations
5. Write a note on metallochromic indicator/pM indicator
6. Explain- how to estimate barium sulphate by gravimetry
7. Write a note on factors affecting purity of precipitation.
8. Write a note on Diazotization titration.
9. What is gravimetric analysis? Explain merits, demerits and application of gravimetric analysis
10. Discuss about co-precipitation and post precipitation
UNIT 04
1. Enlist redox titration in which starch act as an indicator and explain any one in detail
2. Define oxidizing agent and reducing agent with example and explain Redox indicator in detail
3. Describe a note on theory of redox titrations.
4. Write preparation and standardization of cerric ammonium sulphate
5. Difference between Iodimetry titration and Iodometry titration.
UNIT 05
1. Enlist various electrodes used in potentiometry. Explain NHE in detail
2. Write a note on potentiometric titrations
3. What is reference electrode? Mention the type of reference electrodes. Describe in detail of SCE.
4. Describe factor affecting conductance
5. Briefly explain the applications of conductometry.
6. Define: Polarography, Limiting current, Diffusion current, Migration current, Residual current
7. Explain Dropping Mercury Electrode (DME) in detail
8. Write a detail note on end point determination of potentiometric titration
9. Write a note on conductometric titrations
10. Explain principle and applications of polarimetry
11. Discuss in detail different component of polarogram
Comments:
1. Give comment on following
Starch indicator should be added toward the end point in iodometric titration.
Mohr’s titration carried out in acidic media.
2. Differentiate between
Differentiating and leveling effect
Iodometry and Iodimetry
