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While conducting a review of the Braxton Reformatory for Boys, Cal becomes focused upon the case of one particular boy.

Shrewish Alice Nichols seeks to employ Cal to help find her husband more than two weeks after the man went missing. A short time later the husband is found murdered.

A shady real estate developer is trying to strong-arm property owners into selling their land, and Kenny is hired to intercede - by a young woman who has been dead for twenty years.

A man injured in a hit and run accident staggers into Rex and Cal's office. He appears to be suffering from amnesia, but even after people come forward to identify him, some still have doubts.

Cal sets out to prove an old friend is innocent of murder and becomes convinced that the killing is somehow gangland related.

Posing as a journalist, Rex accompanies an expedition into the jungles of San Marco in search of the wreckage of a plane that crashed carrying a South American dictator and a mysterious cargo.

When another singer at her nightclub is murdered, Lusti Weather becomes the prime suspect.

After a close personal friend of Rex is found murdered. He agrees to go undercover into jail to try and crack the alibi of the man he thinks responsible.

Rex is best man at a friend's wedding interrupted by a bomb threat meant for the bride's father. Rex and fellow PI, BJ, investigate twin brothers tied to the father's past.

Several people have received invitations to a politico's party, at which someone is supposed to be murdered. The politico hires Rex to get to the bottom of it.

Cal and Kenny are on a riverboat bound for New Orleans to protect a government informant, while others onboard want him dead. But neither faction seems to know what the man looks like.

A rich old woman has collected a group of misfits around her, dreaming that her act of kindness will change their lives. Cal discovers someone is trying to poison her, but who, and more importantly, how?

A family approaches Rex and Cal when they become concerned about a series of voodoo symbols that have been delivered to their home. The family think it is just mischief, but Cal's knowledge of Voodoo suggests far more sinister motives are in play.

Rex Randolph is hired by a jeweler named Raoul Roulas, to fly to the South American country of San Marco and bring back the murderer of his son. Mr. Roulas believes a swindler named Duke Powell killed his son, stole some jewelry, and fled to San Marco where he bought a gambling nightclub. Mr. Roulas' daughter, Amanda, followed Duke to San Marco to get revenge for killing her brother, and takes a job incognito singing in Duke's nightclub until she can get her revenge. Mr. Roulas also wants Rex to bring Amanda home safe and sound . Upon his arrival in San Marco, Rex discovers the facts of the case are quite different.

Kenny becomes involved in a case when it appears one of New Orleans most famous criminals "The Axe Murder" has re-emerged.

Melody is accused of stealing diamonds that were lent to her by a local socialite, but nothing, not even the diamonds, is what it seems to be.

Cal begins to investigate a strange case when a man claims he checked into a hotel with his wife, and the woman appears to have disappeared with out a trace.

Cal is hired to break up a political gang with a stranglehold on a small town, Midas City, but must end his partnership with Rex to avoid suspicion.

Rex is called in when a famous painting "The Lenore" is stolen from a local art gallery. His expertise and cunning are required when a mysterious woman approaches the gallery with an offer to return the painting.

A girl runs away from a girls' school to see her estranged father. The father turns out to be Big Tom Lanza, a prominent mobster. Lanza's enemies try to turn the situation to their advantage. Cal Calhoun has been hired to track down the girl but finds himself in the middle of more than he bargained for. Calhouns soon fins not only the girl but her principal are in peril -- and he may not survive the case, either.

The murder of a circus performer is linked to the disappearance of a chimpanzee.

Cal Calhoun, when he was a police detective, arrested a man for murder. Six hours before the man is to be executed, Calhoun is convinced the man is innocent. Calhoun makes progress and is on the verge of cracking the case when he realizes he's also the victim of deceit. The clock is ticking and Calhoun may lose his own life before he can save the prisoner's life.

Rex goes undercover to investigate the owner of the Cypress Gun Club, and in the process gets framed for the man's murder.

Rex is hired to find out why the legend of a supernatural swamp phantom is being used to scare Cajun workers away from a bayou oil drilling camp.

Rex and Cal unwittingly become embroiled in the plot to assassinate an up and coming politician.