AmiGO 2: Term Details for "nucleolus" (GO:0005730)

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Term Information

Accession: GO:0005730
Name: nucleolus
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. Source: ISBN:0198506732
Comment: None
History: See term history for GO:0005730 at QuickGO
Chem. react.: None
Subset: goslim_chembl; goslim_drosophila; goslim_generic; goslim_plant; goslim_yeast; goslim_candida; goslim_pir
Related: Link to all genes and gene products annotated to nucleolus (excluding "regulates").; Link to all direct and indirect annotations to nucleolus (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for nucleolus (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
CARO:0000006 material anatomical entity
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0110165 cellular anatomical structure
GO:0005575 cellular_component
GO:0043226 organelle
CL:0000000 cell
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0031974 membrane-enclosed lumen
GO:0005622 intracellular anatomical structure
GO:0043231 intracellular membrane-bounded organelle
GO:0043233 organelle lumen
GO:0070013 intracellular organelle lumen
GO:0043228 membraneless organelle
GO:0005634 nucleus
GO:0043232 intracellular membraneless organelle
GO:0031981 nuclear lumen
GO:0005730 nucleolus
GO:0110016 B-WICH complex
GO:0031429 box H/ACA snoRNP complex
GO:0001651 dense fibrillar component
GO:0061773 eNoSc complex
GO:0001650 fibrillar center
GO:0001652 granular component
GO:0034457 Mpp10 complex
GO:0030874 nucleolar chromatin
GO:0101019 nucleolar exosome (RNase complex)
GO:0005655 nucleolar ribonuclease P complex
GO:0070545 PeBoW complex
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome
GO:0030869 RENT complex
GO:0005736 RNA polymerase I complex
GO:0000120 RNA polymerase I transcription regulator complex
GO:0034455 t-UTP complex
GO:0034456 UTP-C complex

Parents of nucleolus (GO:0005730)

subject	relation	object
nucleolus	RO:0002162	Eukaryota (NCBITaxon:2759)
nucleolus	is_a	intracellular membraneless organelle (GO:0043232)
nucleolus	BFO:0000050	nuclear lumen (GO:0031981)

Children of nucleolus (GO:0005730)

subject	relation	object
Mpp10 complex (GO:0034457)	BFO:0000050	nucleolus
nucleologenesis (GO:0017126)	RO:0004008	nucleolus
erythroblast (CL:0000765)	CL:4030045	nucleolus
basophilic myelocyte (CL:0000614)	CL:4030045	nucleolus
nucleolus organization (GO:0007000)	RO:0002592	nucleolus
promyelocyte (CL:0000836)	BFO:0000051	nucleolus
dense fibrillar component (GO:0001651)	BFO:0000050	nucleolus
nucleolar chromatin (GO:0030874)	BFO:0000050	nucleolus
protein localization to nucleolus (GO:1902570)	RO:0002339	nucleolus
RENT complex (GO:0030869)	BFO:0000050	nucleolus
RNA polymerase I transcription regulator complex (GO:0000120)	BFO:0000050	nucleolus
monoblast (CL:0000040)	BFO:0000051	nucleolus
eNoSc complex (GO:0061773)	BFO:0000050	nucleolus
Pwp2p-containing subcomplex of 90S preribosome (GO:0034388)	BFO:0000050	nucleolus
PeBoW complex (GO:0070545)	BFO:0000050	nucleolus
nucleolar ribonuclease P complex (GO:0005655)	BFO:0000050	nucleolus
B-WICH complex (GO:0110016)	BFO:0000050	nucleolus
proerythroblast (CL:0000547)	BFO:0000051	nucleolus
box H/ACA snoRNP complex (GO:0031429)	BFO:0000050	nucleolus
nucleolar exosome (RNase complex) (GO:0101019)	BFO:0000050	nucleolus
RNA polymerase I complex (GO:0005736)	BFO:0000050	nucleolus
fibrillar center (GO:0001650)	BFO:0000050	nucleolus
t-UTP complex (GO:0034455)	BFO:0000050	nucleolus
UTP-C complex (GO:0034456)	BFO:0000050	nucleolus
granular component (GO:0001652)	BFO:0000050	nucleolus

NIF_Subcellular: sao1820400233
Wikipedia: Nucleolus