SLC22A14

SLC22A14
Identifiers
Aliases	SLC22A14, OCTL2, OCTL4, ORCTL4, solute carrier family 22 member 14
External IDs	OMIM: 604048; MGI: 2685974; HomoloGene: 3530; GeneCards: SLC22A14; OMA:SLC22A14 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	38,318,575 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	119,194,619 bp
RNA expression pattern
	Top expressed in
	testicle; ; pancreatic ductal cell; ; lateral nuclear group of thalamus; ; left testis; ; right testis; ; tibialis anterior muscle; ; pars reticulata; ; male germ cell; ; deltoid muscle; ; sperm;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; proximal tubule; ; yolk sac; ; white adipose tissue; ; spleen; ; islet of Langerhans; ; human kidney; ; right kidney;
	More reference expression data
	n/a
Gene ontology
Molecular function	organic cation transmembrane transporter activity; transmembrane transporter activity; inorganic anion exchanger activity; sodium-independent organic anion transmembrane transporter activity;
Cellular component	integral component of membrane; integral component of plasma membrane; membrane;
Biological process	organic cation transport; transmembrane transport; inorganic anion transport; sodium-independent organic anion transport;
	Sources:Amigo / QuickGO
Orthologs
	9389
	382113
	ENSG00000144671
	ENSMUSG00000070280
	Q9Y267
	Q497L9
	NM_004803; NM_001320033
	NM_001037749
	NP_001306962; NP_004794
	NP_001032838
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 22 member 14 is a protein that in humans is encoded by the SLC22A14 gene.^[5]

Function

This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 3. The encoded protein is a transmembrane protein which is thought to transport small molecules and since this protein is conserved among several species, it is suggested to have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000144671 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000070280 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Solute carrier family 22 member 14". Retrieved 2020-01-19.

Function

References

Further reading