GIPC PDZ domain containing family member 1 (Q21118203)

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mammalian protein found in Homo sapiens

GLUT1 C-terminal binding protein
tax interaction protein 2
GAIP C-terminus-interacting protein
PDZ domain-containing protein GIPC1
regulator of G-protein signalling 19 interacting protein 1
IGF-1 receptor interacting protein 1
TIP-2
RGS-GAIP-interacting protein
GIPC1
RGS19-interacting protein 1
Synectin

Language	Label	Description	Also known as
English	GIPC PDZ domain containing family member 1	mammalian protein found in Homo sapiens	GLUT1 C-terminal binding protein tax interaction protein 2 GAIP C-terminus-interacting protein PDZ domain-containing protein GIPC1 regulator of G-protein signalling 19 interacting protein 1 IGF-1 receptor interacting protein 1 TIP-2 RGS-GAIP-interacting protein GIPC1 RGS19-interacting protein 1 Synectin

Statements

1 reference

13 November 2019

UniProt protein ID

PDZ domain-containing protein GIPC1/2/3

2 references

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14908

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/K7EIT0

PDZ superfamily

2 references

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14908

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/K7EIT0

PDZ domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

2 references

13 November 2019

UniProt protein ID

UniProt protein ID

17 September 2016

2 references

13 November 2019

UniProt protein ID

UniProt protein ID

20 March 2016

language of work or name

molecular function

protein binding

determination method or standard

4 references

8 April 2019

GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

8 April 2019

Interactions between GIPC–APPL and GIPC–TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

8 April 2019

PDZ domain protein GIPC interacts with the cytoplasmic tail of melanosomal membrane protein gp75 (tyrosinase-related protein-1)

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

8 April 2019

A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

PDZ domain binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

signaling receptor binding

determination method or standard

1 reference

8 April 2019

CD93 interacts with the PDZ domain-containing adaptor protein GIPC: implications in the modulation of phagocytosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

cadherin binding

determination method or standard

1 reference

17 October 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14908&geneProductId=UniProtKB:O14908

determination method or standard

cadherin binding

determination method or standard

1 reference

8 April 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

determination method or standard

1 reference

8 April 2019

Myo6 facilitates the translocation of endocytic vesicles from cell peripheries

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

endocytic vesicle

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

extracellular exosome

determination method or standard

determination method or standard

3 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

determination method or standard

4 references

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14908&geneProductId=UniProtKB:O14908

determination method or standard

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14908&geneProductId=UniProtKB:O14908

determination method or standard

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14908&geneProductId=UniProtKB:O14908

determination method or standard

17 October 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14908&geneProductId=UniProtKB:O14908

determination method or standard

cytoplasmic vesicle

determination method or standard

1 reference

8 April 2019

Myo6 facilitates the translocation of endocytic vesicles from cell peripheries

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

determination method or standard

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

8 April 2019

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

extracellular exosome

determination method or standard

1 reference

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

Schaffer collateral - CA1 synapse

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

glutamatergic synapse

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

biological process

G protein-coupled receptor signaling pathway

determination method or standard

1 reference

8 April 2019

GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

positive regulation of cytokinesis

determination method or standard

1 reference

8 April 2019

G protein-coupled receptors participate in cytokinesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

positive regulation of melanin biosynthetic process

determination method or standard

1 reference

8 April 2019

Interactions between GIPC–APPL and GIPC–TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

cellular response to interleukin-7

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

regulation of synaptic vesicle exocytosis

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14908

determination method or standard

2 references

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O14908

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/K7EIT0

Identifiers

MeSH descriptor ID

subject named as

GIPC1 protein, human

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

Ensembl protein ID

ENSP00000340698

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000340698

ENSP00000376748

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000376748

ENSP00000376753

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000376753

ENSP00000466747

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466747

ENSP00000467077

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000467077

ENSP00000464879

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000464879

ENSP00000465003

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000465003

ENSP00000466105

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466105

ENSP00000466312

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466312

ENSP00000466624

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466624

ENSP00000468787

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000468787

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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