ZNF16: Difference between revisions

ZNF16
Identifiers
Aliases	ZNF16, HZF1, KOX9, zinc finger protein 16
External IDs	OMIM: 601262; HomoloGene: 56008; GeneCards: ZNF16; OMA:ZNF16 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	144,950,888 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; oocyte; ; ganglionic eminence; ; gastrocnemius muscle; ; muscle of thigh; ; secondary oocyte; ; ventricular zone; ; skin of leg; ; gingival epithelium;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleolus;
Biological process	positive regulation of cell cycle phase transition; positive regulation of kinase activity; cell cycle; negative regulation of apoptotic process; regulation of transcription, DNA-templated; positive regulation of megakaryocyte differentiation; positive regulation of cell division; positive regulation of erythrocyte differentiation; transcription, DNA-templated; positive regulation of cell population proliferation; cellular response to sodium dodecyl sulfate; cell division; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7564
	n/a
	ENSG00000170631
	n/a
	P17020
	n/a
	NM_001029976; NM_006958
	n/a
	NP_001025147; NP_008889
	n/a
	Wikidata
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Latest revision as of 18:02, 13 October 2022

Zinc finger protein 16 is a protein that in humans is encoded by the ZNF16 gene.^[3]

The protein encoded by this gene contains a C2H2 type of zinc finger, and thus may function as a transcription factor. This gene is located in a region close to ZNF7/KOX4, a gene also encoding a zinc finger protein, on chromosome 8. Two alternatively spliced variants, encoding the same protein, have been identified.^[3]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170631 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: ZNF16 zinc finger protein 16".

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Dreier B, Segal DJ, Barbas CF (2000). "Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains". J. Mol. Biol. 303 (4): 489–502. doi:10.1006/jmbi.2000.4133. PMID 11054286.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Rousseau-Merck MF, Duro D, Berger R, Thiesen HJ (1995). "Chromosomal localization of two KOX zinc finger genes on chromosome bands 7q21-q22". Ann. Genet. 38 (2): 81–4. PMID 7486829.
Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID 2288909.

This article on a gene on human chromosome 8 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170631 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: ZNF16 zinc finger protein 16".

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
+{{Short description|Protein-coding gene in the species Homo sapiens}}
 {{Infobox_gene}}
-'''Zinc finger protein 16''' is a [[protein]] that in humans is encoded by the ''ZNF16'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ZNF16 zinc finger protein 16| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7564| accessdate = }}</ref>
+'''Zinc finger protein 16''' is a [[protein]] that in humans is encoded by the ''ZNF16'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ZNF16 zinc finger protein 16| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7564}}</ref>
 The protein encoded by this gene contains a C2H2 type of [[zinc finger]], and thus may function as a [[transcription factor]]. This gene is located in a region close to ZNF7/KOX4, a gene also encoding a zinc finger protein, on [[Chromosome 8 (human)|chromosome 8]]. Two alternatively spliced variants, encoding the same protein, have been identified.<ref name="entrez"/>
@@ Line 11: / Line 12: @@
 *{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
 *{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
-*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
 *{{cite journal  | vauthors=Dreier B, Segal DJ, Barbas CF |title=Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains. |journal=J. Mol. Biol. |volume=303 |issue= 4 |pages= 489–502 |year= 2000 |pmid= 11054286 |doi= 10.1006/jmbi.2000.4133 }}
 *{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  }}
 *{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
-*{{cite journal  | vauthors=Rousseau-Merck MF, Duro D, Berger R, Thiesen HJ |title=Chromosomal localization of two KOX zinc finger genes on chromosome bands 7q21-q22 |journal=Ann. Genet. |volume=38 |issue= 2 |pages= 81–4 |year= 1995 |pmid= 7486829 |doi=  }}
+*{{cite journal  | vauthors=Rousseau-Merck MF, Duro D, Berger R, Thiesen HJ |title=Chromosomal localization of two KOX zinc finger genes on chromosome bands 7q21-q22 |journal=Ann. Genet. |volume=38 |issue= 2 |pages= 81–4 |year= 1995 |pmid= 7486829 }}
-*{{cite journal  | author=Thiesen HJ |title=Multiple genes encoding zinc finger domains are expressed in human T cells |journal=New Biol. |volume=2 |issue= 4 |pages= 363–74 |year= 1991 |pmid= 2288909 |doi=  }}
+*{{cite journal  | author=Thiesen HJ |title=Multiple genes encoding zinc finger domains are expressed in human T cells |journal=New Biol. |volume=2 |issue= 4 |pages= 363–74 |year= 1991 |pmid= 2288909 }}
 {{refend}}

Latest revision as of 18:02, 13 October 2022

References

Further reading