In this video collection, authors of findings published in The Journal of Clinical Investigation present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Video Abstracts Guidelines page.
In this video, DeLisa Fairweather, Aaron H. Abend, and Ingrid He explain that their paper estimates the prevalence of all autoimmune disease in the US, sex- and age-adjusted, with individual estimates for 105 autoimmune diseases.
In this episode, Laura Ondrisova describes how this manuscript examines a non-genetic adaptation to BTK inhibitor therapy in chronic lymphocytic leukemia that involves Akt activation via FoxO1/Rictor axis.
In this episode, Andreas Patsalos and Laszlo Nagy explain that their findings suggest that macrophage subtypes mediated the development of the highly ordered architecture of regenerative tissues, unveiling the principles of the structured yet dynamic nature of regenerative inflammation supporting effective tissue repair.
In this episode, Laszlo Nagy and colleagues, explain that macrophages coordinate tissue repair by promoting regenerative inflammation. They discovered diverse myeloid cell subsets that organize in functional multilayered tissue zones, crucial for effective muscle repair.
In this episode, Rafael Kramann, Konrad Hoeft, and Lars Koch explain that catalytically active ADAMTS12 controls fibrosis by restructuring ECM to enable activation and migration of a distinct injury-responsive fibroblast subset after injury.